Taufiq, Muhammad (2014) Uji kelarutan batu ginjal dalam ekstrak akuades daun alpukat (Persea americana mill) secara in vitro dan analisis kadar kalsium menggunakan spektrofotometri serapan atom. Undergraduate thesis, Universitas Islam Negeri Maulana Malik Ibrahim.
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Abstract
INDONESIA:
Batu ginjal adalah endapan kristal keras yang terbentuk di dalam ginjal atau dalam saluran kemih. Dalam surat an Nahl ayat 11 disebutkan bahwa berbagai macam tumbuhan yang Allah SWT tumbuhkan di alam memiliki banyak manfaat untuk manusia dan makhluk hidup lainnya, Salah satunya adalah tumbuhan alpukat. Daun alpukat memiliki senyawa yang berpotensi untuk melarutkan batu ginjal. Tujuan dari penelitian ini adalah untuk mengetahui berat batu ginjal yang terlarut di dalam ektrak akuades daun alpukat secara in vitro, serta mengetahui kadar kalsium terlarut yang dianalisis menggunakan spektrofotometri serapan atom.
Penelitian ini meliputi preparasi sampel, pembuatan ekstrak akuades daun alpukat dengan variasi 2,5; 5; 10; 15; dan 20 gr/ 100 mL yang dipanaskan sampai mendidih. Analisis kelarutan batu ginjal dengan cara menimbang batu ginjal utuh seberat ±100 mg diinkubasi dalam 50 mL ekstrak akuades daun alpukat yang bervariasi, selama 3 jam dan setiap 20 menit dilakukan pengadukan selama 5 menit. Batu ginjal yang tidak larut dipisah dengan cara dekantasi. Batu ginjal tidak larut dikeringkan dan ditimbang untuk mengetahui berat batu ginjal yang terlarut. Filtrat didestruksi dengan HNO3 65 % dan dianalisis dengan spektrofotometri serapan atom untuk mengetahui kadar kalsium yang terlarut. Ekstrak daun alpukat diuji fitokimia dengan uji reagen.
Hasil penelitian menunjukkan semakin banyak daun alpukat maka warnanya semakin pekat, uji reagen menunjukkan daun alpukat mengandung flavonoid dan tanin. Massa batu ginjal yang dapat larut pada variasi ekstrak daun alpukat 2,5; 5; 10; 15; dan 20 gr/ 100 mL secara berturut-turut adalah 2,40; 11,20; 21,42; 24,47; dan 33,33 mg dan kadar kalsium terlarut secara berturut-turut adalah 4,25; 185,32; 232,87; 239,49; dan 262,77 mg/L. Jadi semakin pekat ekstrak akuades daun alpukat maka semakin besar pula kadar kalsium yang terlarut. Hasil penelitian ini menunjukkan bahwa daun alpukat berpotensi untuk mengobati penyakit batu ginjal. Dalam Hadist Nabi SAW menyatakan” Tidaklah Allah SWT menurunkan penyakit melainkan Dia menurunkan obatnya”.
ENGLISH:
Kidney stones are hard mineral crystals that formed in the kidneys or the urete. In the surah of An-Nahl verse 11 is mentioned that variety of plants that grown by Allah has many benefits for humans and other living creatures, one of them is avocado tree. Avocado leaves have potential compounds which be able to dissolve kidney stones. The purposes of this research were to determine the weight of kidney stones dissolved in aquades extract of the avocado leaves by in vitro, and the concentration of calcium dissolved using an atomic absorption spectrophotometer analysis.
This research includes sample preparation of avocado leaves aquades extract by various concentration 2,5; 5; 10; 15; and 20 g/100 mL were heated until boiling. Analysis of kidney stones solubility by weighing ± 100 mg were incubated on 50 mL of various aquades extract of avocado leaves for 3 hours and shaked for 5 minutes in every 20 minutes. The undissolved kidney stones were separated by decantation method, dried and weighted for determining weight of dissolved kidney stones. Filtrate was destructed by 65% HNO3 and the concentration of calcium was analyzed by atomic absorption spectrophotometry. Avocado leaves extract were phytochemicals tested with reagents test to find the phytochem-compound.
The result of this research showed that increasing weight of avocado leaves give increasing intense of colour extract. The exctracts contain of flavonoid and tannin.the test reagent showed avocadoleaves contain flavonoids and tannins. The mass of kidney stones dissolved in the variation of avocado leaves extract 2,5; 5; 10; 15; and 20 g/100 mL are 2, 40; 11,20; 21,42; 24,47; and 33,33 mg respectively. Calcium levels of avocado extract are 4,25; 185,32; 232,87; 239,49; and 262,77 mg/L. The increasing of concentrated avocado leaves extract aquades gave the increasing of the concentration of dissolved calcium. The results of this research indicate that the avocado leaves have the potential to treat kidney stones. In a the Hadith Prophet Muhammad declared "God does not give a disease but he gives a medicine".
Item Type: | Thesis (Undergraduate) | |||||||||
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Supervisor: | Dewi, Diana Candra and Fauziyah, Begum | |||||||||
Contributors: |
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Keywords: | Batu Ginjal; Kalsium; Daun Alpukat; Kelarutan; Kidney Stones; Calciums; Avocado Leaves; Solubility | |||||||||
Departement: | Fakultas Sains dan Teknologi > Jurusan Kimia | |||||||||
Depositing User: | Imam Rohmanu | |||||||||
Date Deposited: | 13 Oct 2017 14:34 | |||||||||
Last Modified: | 13 Oct 2017 14:34 | |||||||||
URI: | http://etheses.uin-malang.ac.id/id/eprint/8247 |
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