Khotimah, Husnul (2019) Aktivitas antibakteri ekstrak etanol 70% daun legundi (Vitex trifolia Linn.) terhadap pertumbuhan bakteri Salmonella typhi. Undergraduate thesis, Universitas Islam Negeri Maulana Malik Ibrahim.
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Abstract
ENGLISH:
Legundi leaves (Vitex trifolia L.) are plants that contain active compounds flavonoids, alkaloids, tannins, saponins, steroids, anthraquinones and anthocyanins that have antibacterial activity of Salmonella typhi. The aim of this study was to determine the antibacterial activity and to determine the Minimum Inhibitory Concentration (MIC) of 70% ethanol extract of legundi leaves on the growth of S. typhi bacteria. This study used 70% ethanol extract of legundi leaves with a concentration of 5%, 10%, 15%, 20% (b/v) and positive control (Chloramphenicol 30 mg / ml). The method used a paper disk. Data obtained in the form of an inhibition zone diameter. The results of this study indicate that the four variations in the concentration of 70% ethanol extract of legundi leaves have antibacterial activity on the growth of S. typhi as indicated by inhibition zone diameters of 1.96 mm; 2.1 mm; 2.21 mm; and 2.37 mm. The results of the MIC of ethanol extract 70% of legundi leaves were obtained at a concentration of 5% with an inhibition zone diameter of 1.96 mm. To find out the differences between variations, a statistical test was performed used ANOVA. The results showed no significant difference with a P-value of > 0.05.
INDONESIA:
Daun legundi (Vitex trifolia L.) merupakan tanaman yang memiliki kandungan senyawa aktif flavonoid, alkaloid, tannin, saponin, steroid, antrakuinon dan antosianin yang memiliki aktivitas antibakteri Salmonella typhi. Tujuan penelitian ini untuk mengetahui aktivitas antibakteri dan untuk mengetahui Konsentrasi Hambat Minimum (KHM) ekstrak etanol 70% daun legundi terhadap pertumbuhan bakteri S. typhi. Penelitian ini menggunakan ekstrak etanol 70% daun legundi dengan konsentrasi 5%, 10%, 15%, 20% (b/v) dan kontrol positif (Kloramfenikol 30 mg/ml). Metode yang digunakan adalah paper disk. Data yang diperoleh berupa diameter zona hambat. Hasil penelitian ini menunjukkan bahwa keempat variasi konsentrasi ekstrak etanol 70% daun legundi memiliki aktivitas antibakteri terhadap pertumbuhan S. typhi yang ditunjukkan dengan diameter zona hambat masing-masing 1,96 mm; 2,1 mm; 2,21 mm; dan 2,37 mm. Hasil KHM ekstrak etanol 70% daun legundi diperoleh pada konsentrasi 5% dengan diameter zona hambat 1,96 mm. Untuk mengetahui perbedaan antar variasi dilakukan uji statistik menunggunakan ANOVA. Hasil penelitian menunjukkan tidak adanya perbedaan signifikan dengan P-value sebesar > 0,05.
Item Type: | Thesis (Undergraduate) | |||||||||
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Supervisor: | Anggraini, Wirda and Suryadinata, Arief | |||||||||
Contributors: |
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Keywords: | Vitex trifolia L.; Salmonella typhi; Etanol 70%; Konsentrasi Hambat Minimum (KHM); Minimum Inhibitory Concentration (MIC) | |||||||||
Departement: | Fakultas Sains dan Teknologi > Jurusan Farmasi | |||||||||
Depositing User: | Farahaqila Tami | |||||||||
Date Deposited: | 09 Apr 2020 10:09 | |||||||||
Last Modified: | 09 Apr 2020 10:09 | |||||||||
URI: | http://etheses.uin-malang.ac.id/id/eprint/16651 |
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