Hawari, Fathan Luthfi (2019) Aktivitas antibakteri fraksi buah jambu Wer (Prunus persica (L.) Batsch) terhadap pertumbuhan bakteri Shigella Dysenteriae. Undergraduate thesis, Universitas Islam Negeri Maulana Malik Ibrahim.
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Abstract
INDONESIA:
Secara turun temurun masyarakat suku Tengger telah memanfaatkan buah jambu wer (Prunus persica (L.) Batsch) sebagai obat tradisional untuk diare dan sariawan. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri fraksi buah jambu wer terhadap pertumbuhan bakteri Shigella dysenteriae dan untuk mengetahui fraksi manakah yang memiliki aktivitas antibakteri tertinggi. Fraksi didapatkan dari ekstrak etanol 96% buah jambu wer (Prunus persica (L.) Batsch) menggunakan metode ekstraksi cair-cair. Fraksi yang diperoleh diuji aktivitas antibakterinya dengan metode difusi sumuran dan menggunakan Mueller-Hinton Agar (MHA) sebagai media tumbuh bakteri. Hasil yang didapatkan menunjukkan adanya zona hambat pada masing-masing fraksi dengan dosis 3% yaitu fraksi n-heksana sebesar 4,48 mm; fraksi kloroform 3,98 mm; fraksi etil asetat 6,51 mm dan fraksi air 0,98 mm. Dari hasil uji statistik One-Way ANOVA dengan taraf signifikan α=0,05 dapat disimpulkan bahwa fraksi buah Jambu Wer (Prunus persica (L.) Batsch) dengan pelarut etil asetat, kloroform, n-heksan dan air mempunyai aktivitas antibakteri yang secara statistik berbeda terhadap pertumbuhan bakteri Shigella dysenteriae. Dari hasil penelitian juga didapatkan bahwa fraksi buah jambu wer (Prunus persica (L.) Batsch) dengan pelarut etil asetat merupakan fraksi yang memiliki aktivitas antibakteri tertinggi terhadap pertumbuhan bakteri Shigella dysenteriae yaitu sebesar 6,51 mm.
ENGLISH:
From generation to generation, people of Tengger has used the jambu wer (Prunus persica (L.) Batsch) as traditional medicine for diarrheal and thrush disease. This research aims to know the antibacterial activity of jambu wer fruit fraction against the growth of bacteria Shigella dysenteriae and to know which fraction has the highest antibacterial activity. The fraction obtained from 96% ethanol extract of jambu wer (Prunus persica (L.) Batsch) by using a liquid-liquid extraction method. The obtained fraction was tested for antibacterial activity by the method of well diffusion and using Mueller-Hinton Agar (MHA) as the bacteria grow media. The results showed there is an inhibition zone in each fraction with a dose of 3%, namely n-hexane fraction of 4.48 mm; chloroform fraction 3.98 mm; ethyl acetate fraction 6.51 mm and water fraction 0.98 mm. From the One-Way ANOVA statistical test with a significant level of α = 0.05, it can be concluded that the fraction of jambu wer (Prunus persica (L.) Batsch) Fruit with the solvent ethyl acetate, chloroform, n-hexane and water has antibacterial activity that is statistically different from the growth of bacteria Shigella dysenteriae. From the results of the study it was also found that the fraction of jambu wer (Prunus persica (L.) Batsch) Fruit with ethyl acetate solvent was the fraction that had the highest antibacterial activity against the growth of Shigella dysenteriae bacteria which was 6.51 mm.
Item Type: | Thesis (Undergraduate) | |||||||||
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Supervisor: | Bhagawan, Weka Sidha and Dianti, Meilina Ratna | |||||||||
Contributors: |
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Keywords: | Buah Jambu Wer (Prunus persica (L.) Batsch); Fraksi; Antibakteri; Bakteri Shigella dysenteriae; Jambu Wer fruit (Prunus persica (L.) Batsch); Fractionation; Antibacterial; Shigella dysenteriae bacteria | |||||||||
Departement: | Fakultas Sains dan Teknologi > Jurusan Farmasi | |||||||||
Depositing User: | Heni Kurnia Ningsih | |||||||||
Date Deposited: | 24 May 2019 09:11 | |||||||||
Last Modified: | 24 May 2019 09:40 | |||||||||
URI: | http://etheses.uin-malang.ac.id/id/eprint/14320 |
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